Protein Info for GFF895 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: 5-keto-2-deoxygluconokinase (EC 2.7.1.92) / uncharacterized domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 643 TIGR04382: 5-dehydro-2-deoxygluconokinase" amino acids 12 to 336 (325 residues), 417.9 bits, see alignment E=1.3e-129 PF00294: PfkB" amino acids 13 to 328 (316 residues), 147.8 bits, see alignment E=4.8e-47 PF09863: DUF2090" amino acids 331 to 639 (309 residues), 452.5 bits, see alignment E=6.9e-140

Best Hits

KEGG orthology group: K03338, 5-dehydro-2-deoxygluconokinase [EC: 2.7.1.92] (inferred from 100% identity to ecq:ECED1_0311)

Predicted SEED Role

"5-keto-2-deoxygluconokinase (EC 2.7.1.92) / uncharacterized domain" in subsystem Inositol catabolism (EC 2.7.1.92)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.92

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (643 amino acids)

>GFF895 5-keto-2-deoxygluconokinase (EC 2.7.1.92) / uncharacterized domain (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQGLR
SAMLARVGDEHMGRFVREELNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRDNC
ADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVLKALEYAQKHGLRRALDIDYRPV
LWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVRQL
TQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLNDE
SWEQACRYANACGALVVSRHGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVTTR
KQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKMLLLEGARQAALEAGLQNNSGILA
DTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYHPL
DAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDAADQNEQYYPQIVERFYQLGILPD
WWKLPPLSPDRWREISQHIEHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFAVG
RTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWREYRPAR