Protein Info for GFF89 in Pseudomonas sp. DMC3

Annotation: Ferrichrome outer membrane transporter/phage receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 808 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF07660: STN" amino acids 63 to 111 (49 residues), 33.6 bits, see alignment 3.9e-12 PF07715: Plug" amino acids 156 to 254 (99 residues), 65.6 bits, see alignment E=8e-22 TIGR01783: TonB-dependent siderophore receptor" amino acids 157 to 807 (651 residues), 415.1 bits, see alignment E=3e-128 PF00593: TonB_dep_Rec_b-barrel" amino acids 327 to 778 (452 residues), 221.1 bits, see alignment E=7.9e-69

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 92% identity to pfo:Pfl01_5189)

Predicted SEED Role

"Ferrichrome-iron receptor @ Ferric siderophore receptor, TonB dependent"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (808 amino acids)

>GFF89 Ferrichrome outer membrane transporter/phage receptor (Pseudomonas sp. DMC3)
MSRSPDTLLRPSLLAFAIAFGTPLISSPLLAAEQASSVRAYNLPAAPLSTTLNQIASQGG
LALSLNPALAAGKTSAPVNGQYDAAGALRAALRGTGLQLEQSSAGTYTLVAVPEGTLALP
ETSVIGVENFESAWGPVEGYTATRTAAGTKTDTALVEAPRSISVATRQQMDDRSVHSLDD
AVRYMPGITASSYGSDTRADWLRVRGFEPTQFLDGLPLPKGVYANPKQETWNLDRLALLR
GPASSVYGQTPPGGLLDMVSRRPSAEASSEIQLQYGSDNHRQVNFASTGKIDDAGQFLYG
LSGVVRDSGTQVDHVDNKRYNIAPSLTWNIDDDTKLTLLSQFTRDDTGITSQFLPIQGTK
IKSPLGDISHHKNLGDPDWEYYDRTYYALGYAFEHRLNDVWQFKQNLRYTKSDLSFQSLT
PGSYPFTTVDAEGNVGRTSTSVDEDISQFAVDNNFQADFATGDIRHTLLLGLDHQRSNTN
YTSIFGDGLQTNVINPIYGQPIVRPARSTAFYDYNQKTYQTGLYVQDQMALDQWRLTLGG
REDWVHTSTQFINQSDATNTQRDKKFSGNAALSYVFDNGFVPYLSYAESFQPTTGADATS
TGSLKPTEGKQWELGIKYQPPGSKTLLTAAVYDLTQKNVAVNTFVNNVSVTSQTGEVKVK
GLELEAVSDVTDNLKVIAAYTLAKSEVQKGIDKGNRLQLMPNQQASLWTDYTWHAGVLDG
FGIGAGVRYTGNTYGDKANTWLGKADAYTVFDASVHYDLGRLDNSLKGASLAVNATNLFD
KDYISTCDSFYCYYGDQRSVVASATYKW