Protein Info for GFF886 in Variovorax sp. SCN45

Annotation: Protein of unknown function DUF1446

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details PF07287: AtuA" amino acids 21 to 466 (446 residues), 476.2 bits, see alignment E=5e-147

Best Hits

KEGG orthology group: None (inferred from 90% identity to vap:Vapar_2040)

Predicted SEED Role

"Protein of unknown function DUF1446"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (474 amino acids)

>GFF886 Protein of unknown function DUF1446 (Variovorax sp. SCN45)
MMGGCLQCGSMTSTAATPTLLIGCAAGFSGDRTDAAGPVVDTLIARLAQGPAGRRAFLIF
ETLAERTLALAQLRRRTNPDAGYEPLLDDMLRPVLARCLAHGIRIVSNFGAANPRAAARH
IARMARELGASAPRIAVVEGDDLSGAEHRAVLGEALGARMEGLSVVSANAYIGAEPIAAA
LDAGAQIVVCGRVADPSLTVGPAMSHFGWRADDWDRLGRATMAGHLLECGAQVCGGYFAD
PGYKDVPGLESVGFPIAEIDADGGCVIGKADGTGGLVTEATVKEQLLYEVHDPAAYLTPD
VVADISDAEVRALPGSDRVELRGVRGHARPGNYKVNVCHEGGWLAEGEISYAGPRAEARA
RLATDVLKKRLDGLALRVDLIGALSILGDDAGRALADTPDSGLRDVRLRVAATHADRAQA
ERLGREVMALYTCGPAGGGGVRTALTPRLNTLSCLLSREAVPVRFTLLTQEELA