Protein Info for GFF855 in Xanthobacter sp. DMC5

Annotation: Deoxyguanosinetriphosphate triphosphohydrolase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 TIGR01353: putative dGTPase" amino acids 32 to 394 (363 residues), 331.5 bits, see alignment E=5.1e-103 PF01966: HD" amino acids 69 to 176 (108 residues), 49.8 bits, see alignment E=4e-17 PF13286: HD_assoc" amino acids 302 to 392 (91 residues), 106.2 bits, see alignment E=1.1e-34

Best Hits

Swiss-Prot: 74% identical to DGTL1_AZOC5: Deoxyguanosinetriphosphate triphosphohydrolase-like protein (AZC_2807) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: K01129, dGTPase [EC: 3.1.5.1] (inferred from 86% identity to xau:Xaut_4244)

Predicted SEED Role

"Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1)" in subsystem Purine conversions (EC 3.1.5.1)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>GFF855 Deoxyguanosinetriphosphate triphosphohydrolase-like protein (Xanthobacter sp. DMC5)
MAVSGATPRVAWACEAERSRGRLVPEPEMPPRSPFRRDCDRIIHSTAFRRLKQKTQVFVF
NEGDHYRTRLTHTLEVVQVARSIARALGLDEDLAEALALAHDLGHPPFAHAGERALDACM
AGQGGFDHNAQSLRVVTRIEGRYAAFDGLNLTWETLEGIAKHNGPLTDREGNGIGRYSDG
LPHAIRVHSAQQDLELWSHASAEAQVAAISDDIAYDVHDLDDGLRARMFTLDDIAGLPLV
GEALASVRGRYPGLDVPRTVNEVLRLVITLLIEDVVAESTRRAQAAGVASAEDVRALGTP
IVAFSDAMRQKEKALKGFLFPRMYRHERVNRIMAEAQGVIRDLFAYFINRPKDLPPSWQD
GIETLEGERLARRVCDYIAGMTDRYALDQHARFFDSTPDLR