Protein Info for GFF854 in Sphingobium sp. HT1-2

Annotation: Transcriptional regulator, LacI family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 PF01381: HTH_3" amino acids 2 to 40 (39 residues), 25.3 bits, see alignment 3.3e-09 PF00356: LacI" amino acids 10 to 55 (46 residues), 54.7 bits, see alignment 1.8e-18 PF00532: Peripla_BP_1" amino acids 67 to 284 (218 residues), 72.5 bits, see alignment E=1.1e-23 PF13407: Peripla_BP_4" amino acids 69 to 285 (217 residues), 36.5 bits, see alignment E=1e-12 PF13377: Peripla_BP_3" amino acids 179 to 338 (160 residues), 99 bits, see alignment E=8.1e-32

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 41% identity to psu:Psesu_2928)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (344 amino acids)

>GFF854 Transcriptional regulator, LacI family (Sphingobium sp. HT1-2)
MARRRENGVTIRAVAERAGVSAMTVSNVINGAGRASATTVATVQAAIAELGYVPNLAARR
LAKARATTVGLIYSNRRTPFLDAVLVGSLRATNANGLQLILRDGDGVTLDEAERIAQELV
RSGADALLLIPPFAEQLSGSAILPALGVPFAAIATGTPLSGISTVRIDNQAAMEALTRRV
IADGHRRIAYVAGPDHYSVVAARLDGFYAALQDAGLRVDDSLIVEHSAFDHASGMAAAQA
LLARPDRPTAILCSSDDLAAGVIAQAGQMGLNLPHDLSVTGFDDTILASRVWPPLTVIRQ
PVEDMAFRATQCLIGALGKGGMRVSDEIFDHQLVQRASIAPAST