Protein Info for GFF841 in Methylophilus sp. DMC18

Annotation: Protein RecA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 TIGR02012: protein RecA" amino acids 4 to 324 (321 residues), 574.9 bits, see alignment E=2.4e-177 PF00154: RecA" amino acids 7 to 269 (263 residues), 484.1 bits, see alignment E=2.2e-149 PF08423: Rad51" amino acids 39 to 228 (190 residues), 35 bits, see alignment E=1.9e-12 PF21096: RecA_C" amino acids 272 to 327 (56 residues), 92.3 bits, see alignment E=3.2e-30

Best Hits

Swiss-Prot: 94% identical to RECA_METCL: Protein RecA (recA) from Methylomonas clara

KEGG orthology group: K03553, recombination protein RecA (inferred from 92% identity to mmb:Mmol_1903)

MetaCyc: 75% identical to DNA recombination/repair protein RecA (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"RecA protein" in subsystem DNA-replication or DNA repair, bacterial or DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>GFF841 Protein RecA (Methylophilus sp. DMC18)
MDDNKSKALAAALSQIEKQFGKGSIMRMGDADIGEDLQVVSTGSLGLDIALGVGGLPRGR
IVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDPQYASKLGVNVPDLLISQPD
TGEQALEIADMLVRSGSVDIVVVDSVAALTPRAEIEGEMGDSHMGLQARLMSQALRKLTG
NIKRTNTLVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKKGDEVIGS
ETKVKVIKNKVAPPFKQAEFDIMYGEGISRLGEIIELGVNLKMVEKAGAWFSYNGEKIGQ
GKENAKEFLREHPEIAAEIEAKIRANAKVLADILPSARGEDD