Protein Info for GFF828 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Hypothetical ATP-binding protein UPF0042, contains P-loop

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 PF03668: RapZ-like_N" amino acids 9 to 171 (163 residues), 151.6 bits, see alignment E=1.6e-48 PF22740: PapZ_C" amino acids 176 to 292 (117 residues), 149 bits, see alignment E=7.3e-48

Best Hits

Swiss-Prot: 65% identical to Y1300_POLSJ: Nucleotide-binding protein Bpro_1300 (Bpro_1300) from Polaromonas sp. (strain JS666 / ATCC BAA-500)

KEGG orthology group: K06958, UPF0042 nucleotide-binding protein (inferred from 65% identity to pol:Bpro_1300)

Predicted SEED Role

"Hypothetical ATP-binding protein UPF0042, contains P-loop"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (307 amino acids)

>GFF828 Hypothetical ATP-binding protein UPF0042, contains P-loop (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNPIDDTPIHLVLITGMSGSGKTVALTALEDVGFYCVDNLPPELLESFIDLEQSNRAARV
AIAMDVRSAAALPGLPRRLAQLQRRAHRPVHLTTVFLDATTDTLVRRFSETRRLHPLSLK
RSQDQHRALTDAIEHERELLAELREQALVLDTSLIRPTRLRSQIKDLLGTTQAPLTLVFE
SFAFKRGIPMDADFVFDVRMLPNPHYEPELKPLSGLDAPVATYLAAQPEVVQMEEQITAF
LRHWLPQMLRDHRSYVTVAIGCTGGQHRSVYLVERLADTFAPDWFTRVRHREDDNWPGPA
SQAAELT