Protein Info for GFF816 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: FIG015287: Zinc protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF05193: Peptidase_M16_C" amino acids 200 to 375 (176 residues), 109.2 bits, see alignment E=1.2e-35

Best Hits

KEGG orthology group: K01422, [EC: 3.4.99.-] (inferred from 61% identity to pol:Bpro_1280)

Predicted SEED Role

"FIG015287: Zinc protease"

Isozymes

Compare fitness of predicted isozymes for: 3.4.99.-

Use Curated BLAST to search for 3.4.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (445 amino acids)

>GFF816 FIG015287: Zinc protease (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTLFTLIRRTLLALPLLSALGTAQATIPIEQWAHASGARVHLIASPTIPMLDVQIDFDGG
RRRDPAAQAGLASATAGLLSGGVAAQAGLPALDENQLSEAWADLGAQFGAQITLDRFSVS
LRTLTEPDLLDRAVALAARQLAAPAWPERVWQRDRERMLAALVEAENRPATQAGRAFGRA
VYGGHPYGYRAEADTLKAIRVADMRAFYRRHVASCRAQVSMVGAVDRATADRIVDRLMAA
VQPHGCTALPELPPVQPLAKAVDERLPFAAAQAQVIIGQPGVARADPDFFALYVGNYVLG
GGGFVSRLMTEVREKRGLTYGVSSYFLTARQAGAFQIALTTRPDQAAQAVDVVREVVREF
VAKGPTEAELQAAKDYLINGEALRLDSNRKLLDNVANIAWNDLPLDYLETWTGQIERLSV
ADIQRAFSRVLQPERMVTVVVGARP