Protein Info for GFF807 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Selenide,water dikinase (EC 2.7.9.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 TIGR00476: selenide, water dikinase" amino acids 17 to 326 (310 residues), 428.8 bits, see alignment E=5.9e-133 PF00586: AIRS" amino acids 60 to 167 (108 residues), 93 bits, see alignment E=1.6e-30 PF02769: AIRS_C" amino acids 179 to 356 (178 residues), 73.4 bits, see alignment E=2.4e-24

Best Hits

Swiss-Prot: 72% identical to SELD_BURPS: Selenide, water dikinase (selD) from Burkholderia pseudomallei (strain K96243)

KEGG orthology group: K01008, selenide, water dikinase [EC: 2.7.9.3] (inferred from 79% identity to rfr:Rfer_2844)

Predicted SEED Role

"Selenide,water dikinase (EC 2.7.9.3)" in subsystem Selenocysteine metabolism (EC 2.7.9.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.9.3

Use Curated BLAST to search for 2.7.9.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (361 amino acids)

>GFF807 Selenide,water dikinase (EC 2.7.9.3) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MAGMTTPTPSSPRAEPRLTSLSHGGGCGCKIAPGVLSDILKGTSAMPIPKELLVGIETAD
DAAVYRLNDEQALIATTDFFMPIVDDPFDFGRIAATNAISDVYAMGGTPIMALALVGMPI
NVLSTETIGRILAGGQSVCQAAGIPIAGGHTIDSVEPIYGLVALGLVHPRRVKRNADARV
GDRLVLGKPLGVGVLSAALKKDTLPAAGYAQMIDHTTKLNTAGPDLAALEGVHALTDVTG
FGLAGHALEMARGSATTVHLDMARVPLIEGVRGLASAGMVTGASGRNWAAYGHEVRLGAG
LQPVDQALLSDPQTSGGLLVACAPEAVADVLAVFYRHGFGAAAEIGEVGAASADGVRLRV
N