Protein Info for PS417_04025 in Pseudomonas simiae WCS417

Annotation: glycine/betaine ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 transmembrane" amino acids 9 to 28 (20 residues), see Phobius details amino acids 40 to 67 (28 residues), see Phobius details amino acids 89 to 119 (31 residues), see Phobius details amino acids 156 to 175 (20 residues), see Phobius details amino acids 178 to 199 (22 residues), see Phobius details amino acids 205 to 230 (26 residues), see Phobius details PF00528: BPD_transp_1" amino acids 60 to 236 (177 residues), 75.4 bits, see alignment E=2.6e-25

Best Hits

Swiss-Prot: 63% identical to OSMY_SALTY: Osmoprotectant import permease protein OsmY (osmY) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K05846, osmoprotectant transport system permease protein (inferred from 99% identity to pfs:PFLU0815)

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TZK1 at UniProt or InterPro

Protein Sequence (238 amino acids)

>PS417_04025 glycine/betaine ABC transporter permease (Pseudomonas simiae WCS417)
MAIRYGKGLIGGAVVVALLALLVHWIGINTIELYRDDLLFYLQAHLILVLVSMLAALVVG
IPAGILLSRPNMVGRAERFMQIFNIGNTVPPLAVLAIALGVLGIGSGPAIFALFLASLLP
IVRNTYEGLKNVQGSLKEAAVGIGMTPRQVLFRVELPNAVPIIIGGVRVALAINVGTAPL
AFLIGANSLGSLIFPGIALNNQPQLLLGAACTALLALLLDGLVTMASRLWLERGLRPS