Protein Info for GFF7710 in Variovorax sp. SCN45

Annotation: ATP-dependent protease subunit HslV (EC 3.4.25.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 147 PF00227: Proteasome" amino acids 20 to 79 (60 residues), 42.6 bits, see alignment E=5.6e-15 PF03621: MbtH" amino acids 76 to 122 (47 residues), 72.8 bits, see alignment E=1.2e-24

Best Hits

Predicted SEED Role

"ATP-dependent protease HslV (EC 3.4.25.-)" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent (EC 3.4.25.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.25.-

Use Curated BLAST to search for 3.4.25.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (147 amino acids)

>GFF7710 ATP-dependent protease subunit HslV (EC 3.4.25.2) (Variovorax sp. SCN45)
PPSKGYPPEVAMDPSQNPNVFHATTIVSVRRDGRVAIAGDGQVTLGHTVMKSNARKVRRL
GRDGQVLAGFAGAAADASQDFIVLINDEEQYSLWSASIAIPAGWRTTYGPAAKQACLDYV
DEVWKDLTPRSVRLRLQEAADRARNGG