Protein Info for GFF769 in Variovorax sp. SCN45

Annotation: Conserved TM helix

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 transmembrane" amino acids 15 to 39 (25 residues), see Phobius details amino acids 81 to 107 (27 residues), see Phobius details amino acids 113 to 134 (22 residues), see Phobius details amino acids 155 to 174 (20 residues), see Phobius details amino acids 186 to 206 (21 residues), see Phobius details PF05552: MS_channel_1st_1" amino acids 9 to 57 (49 residues), 51 bits, see alignment 5.3e-18 amino acids 106 to 150 (45 residues), 33.8 bits, see alignment 1.3e-12

Best Hits

KEGG orthology group: None (inferred from 89% identity to vpe:Varpa_3006)

Predicted SEED Role

"Small-conductance mechanosensitive channel"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (260 amino acids)

>GFF769 Conserved TM helix (Variovorax sp. SCN45)
MENFGIHLEPLRAILYQVGAFIPRLLVALVVVFVGWLIAKAARFAVTKALRAINFNVLTE
RAGLDNFLRQGGLAGDTSSLFGILAYWLVILASLLIAFNGMGLSYIADLLGRIVWFVPNV
FVALLVLAFGSYFAKFVGDAVGSYFRGVKMQDAMLFAKVAQYAVMAFVILIALDQIKVGG
DIVRESFLVILAGVVFALALAFGLAGKDWAKAQIERWWPRQQQLTKTTGTGREGPGAAPT
PINPNTNTAAPPRFDDRPPR