Protein Info for GFF754 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 642 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 317 to 338 (22 residues), see Phobius details PF08376: NIT" amino acids 60 to 302 (243 residues), 59.8 bits, see alignment E=8e-20 PF00672: HAMP" amino acids 338 to 388 (51 residues), 41.7 bits, see alignment 1.8e-14 PF00015: MCPsignal" amino acids 453 to 607 (155 residues), 181.9 bits, see alignment E=1.5e-57

Best Hits

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (642 amino acids)

>GFF754 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSSLIRNLRLVHKLVLLGLIAALLVAVPLTAYVRDALSGLAAIESERQGLAPSRSLLEVV
RLAQIHRGMTATVLGGKADAEPQRQARADEVQQAVQRFETLLASDVDDARIRRDWQAIAE
QWQSLSQAVAARGVTGPESFARHTAMIAGLIELNDRVSDHFGLTSDPDKSTYFLIIGTLQ
QMPRLTEMLGQARARGSALLVRQSATPEEKAQIASLVERARVGVRELDISLEKAFEHDAT
LKTRLAAAHAQARSEFEGALKLAREQIVEAPALQYASADYFKATTAAIDGMYGLSDRATK
ELGVEIDSRYTEQRGELAWVLSTIAALLSAGVAFAIVIGRSITRPAELARTVAARVAAGD
LSQAVPPGGGDEMGQLLQAMSTMQAELTRVVGSVRGNAEGVAAASSQIAQGNHDLSARTE
QQASALEETAASMEELSSTVKLNAENAQQANRLAISASEVATQGGDVVAQVVDMMKGIND
SSRQIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRSLAQRSAAAAKE
IKGLIGVSVDRVEQGTALVDQAGSTMSEVVSSIRRVTDIVGEISAASREQSDGVSQVGEA
VTQMDQATQQNAALVEESAAAAQSLKSQADQLVQAVAAFRLA