Protein Info for GFF7409 in Variovorax sp. SCN45

Annotation: ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) / ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 PF00005: ABC_tran" amino acids 34 to 191 (158 residues), 111.8 bits, see alignment E=2.5e-35 amino acids 342 to 492 (151 residues), 124.2 bits, see alignment E=3.7e-39 PF08352: oligo_HPY" amino acids 242 to 274 (33 residues), 18.9 bits, see alignment (E = 9.5e-07) amino acids 544 to 575 (32 residues), 24.6 bits, see alignment (E = 1.6e-08)

Best Hits

KEGG orthology group: K13892, glutathione transport system ATP-binding protein (inferred from 70% identity to put:PT7_1963)

Predicted SEED Role

"Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (577 amino acids)

>GFF7409 ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) / ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) (Variovorax sp. SCN45)
MTLEQVQAKAPPLLDVRGLDVFFLGSNGPVQAVRGLDLTLQRGETLALVGESGCGKSTTA
LALLRLLAPGAVLRGSIQFDGRDILALSPAQLREVRGREISMIFQEPMTSLNPVHTIGTQ
IEETLRRHEKLSALAARKRAIELLDLVRIPEPHQRIDDHPHNLSGGQRQRVMIAMAVACK
PRLLVADEPTTALDVTIQAQILELLDGLRRELDMALLLITHDLGLVAQWADRVAVMYGGE
KVEEASTSRLFAAPSHAYTRGLLGASLHAGSALHYVDARLPEIQTRLDAATGERSFALHV
PEPNSKVRALPVRTAAAEPLLSVQDLRTDYPKRGGGVLHAVDGVSFDIRAGETVGLVGES
GCGKSTLSRTLLRLVNPASGRIVFDGTDIAQLSEKALKPWRRRVQMVFQDPYASLNPRRS
VFDIIESVLKVHGVADRAERRNRIAAILERVGLPADAGRRFPNEFSGGQRQRIGIARALV
LRPSLVVLDEPVSALDVSVQAQILNLLVELKEDFGLSYLFISHDLSVVRYIADRVMVMSK
GQIVETGSHRDIWDRPQHPYTRSLIAAVPGAEQRKAA