Protein Info for GFF740 in Variovorax sp. SCN45

Annotation: Uncharacterized protein YdcJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: None (inferred from 66% identity to dac:Daci_5663)

MetaCyc: 59% identical to 2-oxoadipate dioxygenase/decarboxylase (Pseudomonas putida KT2440)
RXN-21282 [EC: 1.13.11.93]

Predicted SEED Role

"FIG00960493: hypothetical protein"

MetaCyc Pathways

L-lysine degradation V (3/9 steps found)
superpathway of L-lysine degradation (12/43 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.13.11.93

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (459 amino acids)

>GFF740 Uncharacterized protein YdcJ (Variovorax sp. SCN45)
MNDTTFLSSDEIRSLFSRRMSEMYREEVPLYGDLLDVVANVNADSMREPTLLAHLRKNGE
LERIDVERHGAIRLGKPEELATIRRLFKVMGMAPVGYYDLSVAGVPVHSTAFRPVTDASL
SNNPFRVFTSLLRLELIEDLALRAEVQQILARRNIFTPRALALIEQAEKAGGLTAAEAEE
FVAQALETFRWHSEATVSKATYDKLLAAHRLIADVACFKGPHINHLTPRTLNIDDAQVDM
TRRGMSAKDVIEGPPRRKVPILLRQTSFRALQERVAFVGESEGEAGTHTARFGEIEQRGV
ALTRKGRALYDALLSRVRDANGAGNAGADYQARLNAAFNDFPDDLKTMREEGLGFFRYAL
TDKGRAANQDALGAKPLHALVDEGWLEAEPITYEDFLPVSAAGIFQSNLGADEQKSYAAN
SAQAVFEAALGATVQDEIALYEEAQARSLKEAVPFLSAH