Protein Info for GFF739 in Variovorax sp. SCN45

Annotation: BUG/TctC family periplasmic protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF03401: TctC" amino acids 58 to 330 (273 residues), 340.4 bits, see alignment E=3.3e-106

Best Hits

Swiss-Prot: 39% identical to YCLC_PSEPU: UPF0065 protein in clcB-clcD intergenic region from Pseudomonas putida

KEGG orthology group: None (inferred from 63% identity to ajs:Ajs_3546)

Predicted SEED Role

"Tricarboxylate transport protein TctC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>GFF739 BUG/TctC family periplasmic protein (Variovorax sp. SCN45)
MPAQTSNHRRALLSLALIAAVGGVALSQPGTAQAENAWPTKAITLVVPFPAGGTTDTMAR
LAGQALSKELGQSVVIDNKPGAGGNIGAQAVARSTPDGYTLLMGTVGTHAINPALYKKMP
YNHLKDFAPVSRVVAVPNVLVVNPSRPYKTVQELIAYARANPDKVTYASSGNGTSIHLVA
ELFKTMTGVKMQHIPYKGSAPALADLMGGQTDIMFDNMPSSISFVKAGKLRPLAVTTATR
SAQLPNVPVLAEAGVPGFDAASWFGLLAPAGTPAAVIQRIDDALIKAMASTELKQKIIEQ
GGDPVAETPEKFSAFIQSETVKWGKIVKDSGASVD