Protein Info for GFF7356 in Variovorax sp. SCN45

Annotation: Branched-chain amino acid ABC transporter, ATP-binding protein LivF (TC 3.A.1.4.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 PF00005: ABC_tran" amino acids 23 to 169 (147 residues), 119.8 bits, see alignment E=2.1e-38 PF12399: BCA_ABC_TP_C" amino acids 222 to 241 (20 residues), 26.4 bits, see alignment (E = 6.3e-10)

Best Hits

Swiss-Prot: 33% identical to LIVF_METJA: Probable branched-chain amino acid transport ATP-binding protein LivF (livF) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K01996, branched-chain amino acid transport system ATP-binding protein (inferred from 62% identity to bpe:BP1650)

Predicted SEED Role

"Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (241 amino acids)

>GFF7356 Branched-chain amino acid ABC transporter, ATP-binding protein LivF (TC 3.A.1.4.1) (Variovorax sp. SCN45)
MSDKEALLSVVDAKSCYGRVEVLHGISLDVFEGEVVAIIGANGAGKTTLMRTISGVQDLS
AGSMRFAGESLDRVPAHRRISRGIAQVPEGRHVFPSLSVEDNLQLGAWSLSRVQRRERAR
MDWAYQAFPILHEKRSIAAGRLSGGQQQMVAIARAMMVRPRLLLLDEPSMGLAPLIVKQV
FEALHALKQQGMTILLIEQNATLALEFANRAYVMETGSVTLEGPAAAVRADPRVQASYLG
S