Protein Info for GFF7325 in Variovorax sp. SCN45

Annotation: Glucans biosynthesis glucosyltransferase H

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 668 transmembrane" amino acids 89 to 109 (21 residues), see Phobius details amino acids 124 to 148 (25 residues), see Phobius details amino acids 450 to 471 (22 residues), see Phobius details amino acids 490 to 511 (22 residues), see Phobius details amino acids 519 to 537 (19 residues), see Phobius details amino acids 543 to 561 (19 residues), see Phobius details amino acids 573 to 597 (25 residues), see Phobius details amino acids 602 to 627 (26 residues), see Phobius details PF00535: Glycos_transf_2" amino acids 173 to 360 (188 residues), 55.9 bits, see alignment E=8.1e-19 PF13506: Glyco_transf_21" amino acids 270 to 422 (153 residues), 22.2 bits, see alignment E=1.3e-08 PF13632: Glyco_trans_2_3" amino acids 274 to 499 (226 residues), 63.9 bits, see alignment E=2.9e-21

Best Hits

KEGG orthology group: K03669, membrane glycosyltransferase [EC: 2.4.1.-] (inferred from 94% identity to vpe:Varpa_1020)

Predicted SEED Role

"Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-)" (EC 2.4.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.-

Use Curated BLAST to search for 2.4.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (668 amino acids)

>GFF7325 Glucans biosynthesis glucosyltransferase H (Variovorax sp. SCN45)
MKPNDFSQLNVLAETDFAHRSPVREERHPNAVTAPPINRGSMTPRPWRGFWNSLGTAALV
KLGAGRDTEAKAATEVKQPWQRAAARRRLAFMMLTLLSTVIASSLFASVQPDYDNVWLEY
GQIGLYGLLSGWVVTGFVTALMGFYVSVRGDKHALSAKQVVNHPMNPEARTAIIMPICNE
DVATVFAGLRATCESVAATGHAKQFDVFVLSDSYNPETAAAERAAWEDLRAALAESPNQP
QVEVYYRLRTRRTHRKAGNVADFCRRWGKDYRYMVVLDADSVMSGDCLTSMVKLMEANPT
AGIIQTATQAIGHVTLHARAQQFASRVTGRLFTLGMQFWQLGESHYWGHNAIIRVEPFMK
HCALAPIKGTGGMSGGIMSHDFVEAALMRRAGYNVWLVSDLVGSYEQQPPDLLAELQRDR
RWCQGNLQNARLMAEPGIHSVHRAMFVTGTMAYVSAPLWLAFLTLGTALWLSGSSLVSSW
SVLPAELAGLWVWTLCLLFLPRVLGIAAVLMRGEQRQYGGVWGLVKSSVLESGLAIVQAP
VRMLAHSLFVVVALTGIKLDWKSPPREAAAVPWKIAATQLAPMTLVIAMLAVGVAMIDPS
ALIWLMPVGLPLLLAIPLTVLTSQIALGTTLRDRGFLLIPEESRSPAVLRRAWMHAVRLA
RPAALATA