Protein Info for GFF7308 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 407 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 51 to 70 (20 residues), see Phobius details amino acids 82 to 99 (18 residues), see Phobius details amino acids 104 to 129 (26 residues), see Phobius details amino acids 138 to 159 (22 residues), see Phobius details amino acids 166 to 186 (21 residues), see Phobius details amino acids 220 to 241 (22 residues), see Phobius details amino acids 248 to 270 (23 residues), see Phobius details amino acids 281 to 303 (23 residues), see Phobius details amino acids 309 to 333 (25 residues), see Phobius details amino acids 347 to 367 (21 residues), see Phobius details amino acids 373 to 392 (20 residues), see Phobius details PF07690: MFS_1" amino acids 20 to 322 (303 residues), 106.2 bits, see alignment E=8.9e-35 amino acids 220 to 391 (172 residues), 41.3 bits, see alignment E=4.7e-15

Best Hits

Swiss-Prot: 40% identical to YDER_BACSU: Uncharacterized MFS-type transporter YdeR (ydeR) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 77% identity to vap:Vapar_4753)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (407 amino acids)

>GFF7308 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSSIQRTHEGPSNPLIFLLAASAGLAVAALYYSQPMLGVLGPDIGASARAVGFVPTLTQL
GYALGILLLAPLGDRFDRRRIILVKASVLVLALLGAAFSPSVGLLLVASLAIGLSATMAQ
DVVPAAAMLAPEAHRGRIVGTVMTGLLLGILLSRVLSGFVAEHFGWRAMFFVAAASIALI
GAAAARGLPHLRPTTQLGYGALLGSLAKLWKRHGALRRATFAQALLSVGFSAFWSTLAVM
LHGAPFHLGSAAAGAFGLAGAAGALAAPIAGRLADRRGPELVIRLGAALVVVSFAAMLFA
PLMAPAARLWLIVASAIGFDFGLQAALIAHQTIVYGIDPAARSRLNAVFFTGVFVGMAAG
SALGALVLAQWGWPGVALMAALSALGALAVRMWPAAGVKPAVACPAA