Protein Info for GFF7234 in Variovorax sp. SCN45

Annotation: Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 PF02353: CMAS" amino acids 115 to 376 (262 residues), 231.7 bits, see alignment E=2.8e-72 PF13847: Methyltransf_31" amino acids 173 to 253 (81 residues), 31.2 bits, see alignment E=4.3e-11 PF13649: Methyltransf_25" amino acids 178 to 271 (94 residues), 42.7 bits, see alignment E=1.9e-14 PF08242: Methyltransf_12" amino acids 178 to 271 (94 residues), 33.1 bits, see alignment E=1.9e-11 PF08241: Methyltransf_11" amino acids 178 to 272 (95 residues), 36.9 bits, see alignment E=1.2e-12

Best Hits

KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 72% identity to rfr:Rfer_0826)

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)" (EC 2.1.1.79)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.79

Use Curated BLAST to search for 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (408 amino acids)

>GFF7234 Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) (Variovorax sp. SCN45)
MLLSQPLRNMLDDLGRRSAACFAIAMPDGSRHRAGEGEPAFTVVFHTEAALFATATRGHI
GLLEAYFDQEVDVEGDFGAALAAGMAAGFDHRAGAFNGIENSLHELRHSNQDPAHAKANA
RAHYGLGTGFYRLWLDDPLMMYTCGYWPEGTPSLEEAQRRKIDHVCRKILLRPEDRFIDI
GCGFGGFMFRAQEKTGATGVGLNTTTEQVEWLRNEIERRGLEASLQVREADFRDVDEQYD
KVVSIGTLEHAGRDQLPEVVRAHAEFLKPVGLGILHFIGHVGRFETELFIRKHVFPGGWI
PSLADVIVEMERNGLEVLDIENLRRHYAPTLDAWADRFEKHWPAIQRLDPQRFDERFRRV
WRTYLVGCAEMFRSDAGYTHLFQVVFSKGNVTPRSYPMDRAHLYEPKP