Protein Info for GFF7190 in Variovorax sp. SCN45

Annotation: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 TIGR03860: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family" amino acids 9 to 434 (426 residues), 519.9 bits, see alignment E=2.4e-160 PF00296: Bac_luciferase" amino acids 26 to 392 (367 residues), 159.9 bits, see alignment E=5e-51

Best Hits

KEGG orthology group: None (inferred from 57% identity to bmj:BMULJ_05134)

Predicted SEED Role

"Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (456 amino acids)

>GFF7190 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases (Variovorax sp. SCN45)
MAFRRPILLNAFDMNTVGHISHGLWRHPRDRSTEYKRLPYWLDLARTLERGLFDGLFLAD
VTGVYDVWGGNADAALRDAIQLPINDPAVLVGAMASVTRHLGFGITATISAEQPHAFARR
MSTLDHLSEGRVGWNIVTGFLDSSARAGGDTATAGHDQRYDRADEFMQLVYQLWESSWDD
DAVIADRARGIYTDPAKVRPIRHEGTYYRLDAVHPCEPSPQRTPLLFQAGASARGTAFAA
RHAEVVFVPNQGLQASAAVVRKLKAAMADAGRDPSSARFVTTLQVVAGSTESEARGRYDD
YRRHARPEAGLVQFSSAIGADLSRHGLDDPVTGGSADAIQSAVASLRRQGAAPTVRQLLA
QMPLGGRHTPVVGTPAQIADEIEAWVDEAGVDGFNLVRTVSPEGLEHFVDLVVPELQRRG
LHKRAYAEGSWREKIFGRASVRPPAVQSARQFTNRP