Protein Info for GFF71 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Predicted secretion system X protein GspD-like

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 690 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF07660: STN" amino acids 208 to 258 (51 residues), 31.2 bits, see alignment 4.7e-11 PF03958: Secretin_N" amino acids 272 to 330 (59 residues), 30.2 bits, see alignment 1.3e-10 PF00263: Secretin" amino acids 416 to 577 (162 residues), 141.7 bits, see alignment E=5.2e-45

Best Hits

KEGG orthology group: K02453, general secretion pathway protein D (inferred from 57% identity to eba:ebA1239)

Predicted SEED Role

"Predicted secretion system X protein GspD-like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (690 amino acids)

>GFF71 Predicted secretion system X protein GspD-like (Hydrogenophaga sp. GW460-11-11-14-LB1)
LNLLPLSSRFAAVLVLAVIAGCATHPAIRESEALMAAGRLDESVTRLEEGLRESGNHNEL
RTIYFRQRDRVSAQLGAQAESERLAGRLDEAQALYQRAQKLDPNNPRLRDGLIALENERR
VAARMVEARALLAKRDNAGAEKVLREVLSLAPTHVEARRALERVRAEAPRPDEPPQALAA
ALGKPITLDFREVQIKQVFDVIARTSGVNFVFDKDVRSDARVTIFVRNASVEEVIGLVLT
TNQLERKLLNDNTLMIYPNTPAKARDYKELVTRSFFLANADVKQAQAMVRTIVKTRDIFI
DEKLNLMIIKDTAEAVRLAERLLSSLDMAEPEVMLDVEVLEVTRSRLQELGLRFPDQIGY
GRLQPNIATTIVNNGVTQSNTTLGGQLAEGYVDLRNRSGLTSFVANPAITLNLRSEAGDG
NTLANPRIRVKNREKAKIHIGDKLPVFTTTSTANVGVSSSVSYLDVGLKLDVEPNVYLDD
EVGIKVQLEVSSVIREVTGPSNSLAYQIGTRSAGTVLRLRDGETQVLAGLINDEERSSAN
RLPGLGDIPAIGRLFSSTRDNNSKTEIVLLITPRIVRNVARPDSNAFNEPAGSEASVGAP
PLQLKSTAPRTLSLSGGGGGAAPRAAAPPAVQAPAAADEAPVEPREPASAAPAPAQDAPA
APPAAPGAPSSVTLTPVAPLAPERPTGQSP