Protein Info for GFF709 in Variovorax sp. SCN45

Annotation: ABC transporter, substrate-binding protein (cluster 2, ribose/xylose/arabinose/galactose)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF13407: Peripla_BP_4" amino acids 83 to 335 (253 residues), 118.5 bits, see alignment E=1.9e-38

Best Hits

KEGG orthology group: None (inferred from 57% identity to scb:SCAB_79461)

Predicted SEED Role

"Ribose ABC transporter, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)" in subsystem Bacterial Chemotaxis (TC 3.A.1.2.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (386 amino acids)

>GFF709 ABC transporter, substrate-binding protein (cluster 2, ribose/xylose/arabinose/galactose) (Variovorax sp. SCN45)
MKSHRSNRRQALRCGVLALAVAAHAGAFAQVANVDVDKEMQEQARLMTATPEGPAGQPWL
QRIGGKTVDTAKYRKKGPYTLCFSNASVGNPWRVVGWNTMQAEVELNKADIKGFEYADAQ
GKDEKQISDIRSLVNSGKCDALIVSPNTSAALTPAVEEACKKLPVVTFDRSVDSLCPVTA
VRSIGGYAWGKVGADFIAANAPKGGKVLVLRTAPGVDLFETRWAAAKKVFDASGLKVVGN
EFVGGDRAKTKATVADYLSRSGKIDAVWVDLGAVSVAVAEAFEDAGQPYPIITGEDQQDY
LQAWKKNGFKGIAPTYPAYQWRTAVIAALKALKGEPLPSPTWILPQPSITAKELPQYVND
KLPPLHYSMCGCEKMPGYPQRWGGKQ