Protein Info for GFF7044 in Variovorax sp. SCN45

Annotation: Inner membrane protein YedI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 302 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details transmembrane" amino acids 81 to 99 (19 residues), see Phobius details amino acids 148 to 166 (19 residues), see Phobius details amino acids 172 to 196 (25 residues), see Phobius details amino acids 224 to 247 (24 residues), see Phobius details amino acids 272 to 294 (23 residues), see Phobius details PF05661: DUF808" amino acids 3 to 290 (288 residues), 373.3 bits, see alignment E=4e-116

Best Hits

Swiss-Prot: 64% identical to YEDI_ECOLI: Inner membrane protein YedI (yedI) from Escherichia coli (strain K12)

KEGG orthology group: K09781, hypothetical protein (inferred from 95% identity to vpe:Varpa_4208)

Predicted SEED Role

"Membrane protein, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (302 amino acids)

>GFF7044 Inner membrane protein YedI (Variovorax sp. SCN45)
MASSLLLLLDDIATVLDDVSVLTKVAAKKTAGVLGDDLALNAQQVSGVRAEREIPVVWAV
CKGSFINKAILVPAALAIGTWLPWLVTPLLMVGGAFLCFEGAEKLAHKFLHKKAHAEDTG
RHEQAVADASVDVVAIEKDKIKGAVRTDFILSAEIIAITLGTVQGQPFTTQLSVLVGIAL
IMTIGVYGLVAGIVKLDDAGLYLSQRAGAASRAVGRGILVAAPWLMKALSVAGTAAMFLV
GGGILVHGVPALGHAVEDWAKATGGVFGTLGSMGVNAGVGVVAGAIVLAVVELVGKLRGK
KA