Protein Info for GFF7021 in Variovorax sp. SCN45

Annotation: ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 345 PF00005: ABC_tran" amino acids 38 to 188 (151 residues), 99.7 bits, see alignment E=2.3e-32 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 238 to 325 (88 residues), 87.2 bits, see alignment E=3e-29 PF08352: oligo_HPY" amino acids 240 to 307 (68 residues), 59.3 bits, see alignment E=3.9e-20

Best Hits

KEGG orthology group: K02032, peptide/nickel transport system ATP-binding protein (inferred from 95% identity to vpe:Varpa_4441)

Predicted SEED Role

"Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (345 amino acids)

>GFF7021 ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) (Variovorax sp. SCN45)
MTFIGKTDTLLSVDDLKVHFPRGKAGWGRTPEVVKAVDGVSFEIRRGTTLAVVGESGSGK
TTTALAVMRLSPVTSGRMRLGDTDLAALRGEALRQARTRMQIIFQDPFSSLNPRERAGAA
VRAPLDLMRVGTPDERTRRVAELFEAVGLRPEQQHLFPHQFSGGQRQRINIARALATNPE
LVVCDEPVSALDIAIRAQILNLLSRLQRELGLTYLFISHDMAVVEHICDDIAVMYLGQIV
ERAPRRSFFARPLHPYSVALMSAVPTVSGGRRRAAHRIKLSGDPPSPIDPPAGCRFAGRC
PVAEPACAAELPPLREVAPDHWVRCRRVDVVDGLPHPPLSIPELP