Protein Info for GFF7006 in Variovorax sp. SCN45

Annotation: Flagellar biosynthesis protein FliR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 52 to 75 (24 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 153 to 176 (24 residues), see Phobius details amino acids 190 to 212 (23 residues), see Phobius details PF01311: Bac_export_1" amino acids 1 to 218 (218 residues), 167.1 bits, see alignment E=2.5e-53

Best Hits

KEGG orthology group: K02421, flagellar biosynthetic protein FliR (inferred from 78% identity to vap:Vapar_2260)

Predicted SEED Role

"Flagellar biosynthesis protein FliR" in subsystem Flagellar motility or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (238 amino acids)

>GFF7006 Flagellar biosynthesis protein FliR (Variovorax sp. SCN45)
MMTPVLYAVPLPATVRVLLVLSLSVALASALTSAAGAPVEWRVLLPAALSELVLGAVLGL
GILLAFGAFTVAGQMLDVQLGFGIAQIMDPVTRRPVPILTTAFAYVAVLVFFLVNGHHAL
LRGIAYSVERFPVGAPWSLAQAVEPVLKQAAGLFSLGFALAAPVVFCILLAEFALGVVGR
NLPQMNMFTMGIPVKIIVGLVALSLWFTGIGGVMTRVYAGIATTWDEIFVSAPPQWGR