Protein Info for GFF6905 in Variovorax sp. SCN45

Annotation: Chloride channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 589 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 70 to 89 (20 residues), see Phobius details amino acids 125 to 137 (13 residues), see Phobius details amino acids 144 to 155 (12 residues), see Phobius details amino acids 167 to 192 (26 residues), see Phobius details amino acids 203 to 221 (19 residues), see Phobius details amino acids 234 to 261 (28 residues), see Phobius details amino acids 275 to 292 (18 residues), see Phobius details amino acids 312 to 333 (22 residues), see Phobius details amino acids 339 to 359 (21 residues), see Phobius details amino acids 366 to 393 (28 residues), see Phobius details amino acids 399 to 418 (20 residues), see Phobius details PF00654: Voltage_CLC" amino acids 81 to 413 (333 residues), 264 bits, see alignment E=2.2e-82 PF00571: CBS" amino acids 519 to 566 (48 residues), 21 bits, see alignment 3.4e-08

Best Hits

KEGG orthology group: None (inferred from 94% identity to vap:Vapar_6375)

Predicted SEED Role

"Chloride channel protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (589 amino acids)

>GFF6905 Chloride channel protein (Variovorax sp. SCN45)
MSTKASSSHPPRGDFALNTRLMRIAVMAAVIGAISTMAARVLLDLIRFFTNLFFFQTLSL
ADRSPAANTLGAWVIAVPVIGGLIVGLVARYGSDKIRGHGIPEAIEAILFGKSRMSPKVA
LLKPLSSGIVIGSGGPFGAEGPIIMTGGAIGSLIAQHFHLTAAERKALLVAGATAGMTAV
FGTPVAAVLLAVELLLFELRPRSLLPVAVACAVAGFTRPLLMDAGPLFPLQTAVPGPLAM
LSCVIAGVLCGALSASLSISLYKVEDWFGKLPLHWMWWPAIGGLAVGIGGWLQPRALGVG
YDVIGDLLHNHLALGVVLALLAVKAVIWVIALGSGTSGGVLAPLLMMGAGLGVVLSHLLP
GNDPMLWPLVCMAATLGGVMRAPLTATIFAFGLTHDSNALLPLLATSAVAYGFTVLTMRR
SILTEKIARRGYHIYREYGIDPLERHSVEEVMTREVRSIDAALPVTRALADYFGEGQAHR
AFPVLRNGAVIGVADRAMLAAVGTRDPIATVGDACADVPLYFALPGENCRAVATRLARHR
LERMPVVKDAQSLVLAGIVSRSDLIKPSLAHFDEEEKRERMRGLPWQSS