Protein Info for GFF6900 in Variovorax sp. SCN45

Annotation: Biofilm PGA synthesis N-glycosyltransferase PgaC (EC 2.4.-.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 16 to 39 (24 residues), see Phobius details amino acids 304 to 329 (26 residues), see Phobius details amino acids 346 to 366 (21 residues), see Phobius details amino acids 378 to 401 (24 residues), see Phobius details TIGR03937: poly-beta-1,6 N-acetyl-D-glucosamine synthase" amino acids 16 to 420 (405 residues), 573.7 bits, see alignment E=1.1e-176 PF13641: Glyco_tranf_2_3" amino acids 61 to 282 (222 residues), 113.1 bits, see alignment E=5.2e-36 PF00535: Glycos_transf_2" amino acids 62 to 229 (168 residues), 118.3 bits, see alignment E=8.9e-38 PF13506: Glyco_transf_21" amino acids 126 to 281 (156 residues), 47.8 bits, see alignment E=3e-16 PF13632: Glyco_trans_2_3" amino acids 142 to 350 (209 residues), 84.8 bits, see alignment E=1.9e-27

Best Hits

KEGG orthology group: K11936, biofilm PGA synthesis N-glycosyltransferase PgaC [EC: 2.4.-.-] (inferred from 55% identity to mms:mma_2647)

Predicted SEED Role

"Biofilm PGA synthesis N-glycosyltransferase PgaC (EC 2.4.-.-)" (EC 2.4.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.-.-

Use Curated BLAST to search for 2.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>GFF6900 Biofilm PGA synthesis N-glycosyltransferase PgaC (EC 2.4.-.-) (Variovorax sp. SCN45)
MTTSHFLAQTLPSLLFGFVFYYPFFMAYVWMAGGLSHAWVFERKRDVDVNPLDLLPSRPL
VTVVVPCFNEVPHLREVIEQLMRSRYPNYEVIAVNDGSTDGTGELLDDMTKEYGRLRVIH
NASNQGKAVGLNTACQLARGEYILGIDGDALVDEDAIAWMLRPMLASERIGAVTGNPRIR
TRTTLLGRMQVGEFSSIIGLIKRSQQLVGTLFTVSGVIAMFRRRAVIDVGFWSPDVLTED
IDMSWKLQLGGWKLRFEPRALCWILMPETLRGLWKQRQRWAIGGIQTMLRNTTRILRLRN
WRMWLVYAEYMTSVVWAYAMAAVLVVSLVRPFLPIESAWHSALLPHWQGTLLAMTCILQM
LLSLWIDRRYDRDLMRYFAGTIWYPIAFWTITMATTVIALPKALIRRRGKRAVWTSPDRG
VSDAP