Protein Info for GFF6873 in Variovorax sp. SCN45

Annotation: Aminotransferase, DegT/DnrJ/EryC1/StrS family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 368 PF01041: DegT_DnrJ_EryC1" amino acids 17 to 364 (348 residues), 337 bits, see alignment E=1.6e-104 PF00155: Aminotran_1_2" amino acids 25 to 166 (142 residues), 28.2 bits, see alignment E=1.1e-10

Best Hits

Swiss-Prot: 63% identical to VIOA_SHIDY: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase (vioA) from Shigella dysenteriae

KEGG orthology group: None (inferred from 75% identity to rme:Rmet_5236)

Predicted SEED Role

"Aminotransferase, DegT/DnrJ/EryC1/StrS family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (368 amino acids)

>GFF6873 Aminotransferase, DegT/DnrJ/EryC1/StrS family (Variovorax sp. SCN45)
MNKPLYVTQPYLPPLDEFLPYLQQIWDNKILTNGGPFHQELEKALCEYLGVEHIALFTNG
TIALVTALQSLRITGEVITTPYSFVATSHSLLWNGIKPVFADVDPHTLNLDPKRIEALIT
PQTTAIMPVHCYGHPCDTRAIQAIADNYNLRVIYDAAHAFGVQDESGSILNHGDMSVLSF
HATKVFNTFEGGAIICKDATTKTRIDQLKNFGHVGEVTVVAPGINGKMSEFNAALGLLQL
KHLHKALDLRRAIDAAYRRLLEDVPGIVCLADAGETVANYAYFPILVGPEFRLSRDGLYE
HLKANGIHPRRYFYPLISEFPMYRGLPTASRDHLPNASRAAERILCLPIYPDLEMSQVER
IVSLIAAA