Protein Info for GFF675 in Xanthobacter sp. DMC5

Annotation: L-cystine transport system permease protein YecS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 transmembrane" amino acids 19 to 41 (23 residues), see Phobius details amino acids 53 to 75 (23 residues), see Phobius details amino acids 86 to 105 (20 residues), see Phobius details amino acids 140 to 164 (25 residues), see Phobius details amino acids 184 to 204 (21 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 11 to 107 (97 residues), 93.3 bits, see alignment E=5.7e-31 PF00528: BPD_transp_1" amino acids 31 to 212 (182 residues), 56 bits, see alignment E=2.3e-19

Best Hits

Swiss-Prot: 37% identical to YCKA_BACSU: Probable amino-acid ABC transporter permease protein YckA (yckA) from Bacillus subtilis (strain 168)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 88% identity to azc:AZC_4406)

MetaCyc: 39% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"polar amino acid ABC transporter, inner membrane subunit"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (217 amino acids)

>GFF675 L-cystine transport system permease protein YecS (Xanthobacter sp. DMC5)
MIRQFTSAEFFFLVSAVRWTLLLSAIAFVGGATLGLVVALARTSPWQWLRATAGAYILVF
QGTPLLMQLFLVFFGATMVGASVDPLAAAAIGLTLNAAAFLGEIWRGCIQAIPKGQWEAS
TALGLHYVTRMREIILPQAAKIAVAPTVGFLVLLVKSTSLASIIGFVELTRAGQIVNNAT
FRPFLVFGIVAAIYFALCWPLSLYARHLEKRFGTVSR