Protein Info for GFF6747 in Variovorax sp. SCN45

Annotation: Glycosyl transferase, family 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 transmembrane" amino acids 273 to 294 (22 residues), see Phobius details amino acids 306 to 331 (26 residues), see Phobius details PF13641: Glyco_tranf_2_3" amino acids 48 to 217 (170 residues), 55.1 bits, see alignment E=1.5e-18 PF00535: Glycos_transf_2" amino acids 50 to 211 (162 residues), 118 bits, see alignment E=6.5e-38

Best Hits

KEGG orthology group: None (inferred from 79% identity to vap:Vapar_5572)

Predicted SEED Role

"Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-)" in subsystem Lipid A-Ara4N pathway ( Polymyxin resistance ) (EC 2.4.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.-.-

Use Curated BLAST to search for 2.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (361 amino acids)

>GFF6747 Glycosyl transferase, family 2 (Variovorax sp. SCN45)
MISSSTARHSRAGAGISSDMAAPAGTPGAPEPLAQSGVPDAPAADARSISCVIPCYNEAA
NLRLMLPLLEDILWATRLRWEIIVVDDGSTDDTAAVAEAWCELAGFRCVSLSRNFGKEAA
LTAGLAAATGDAVVLLDGDLQHSPELIHAMLAQWTAGAEVVYAVRQERSDESRFKQFGSK
LFYNLVNSSDRFEVPKDAGDFRLMDRKVVDALMSMPERSRFMKGLYAWVGFRAVALPYTP
APRAEGTTKFNARRLVGLAIDGLTAFTTWPLRMVSVVGLLLAVPAFGYGTYVTIDHLLFG
NSVSGWTTIVVSLMFFIGIQMISTGIVGEYIARIYEEVKGRPLYVVRREHGKGLESRTGK
P