Protein Info for GFF6746 in Variovorax sp. SCN45

Annotation: dolichyl-phosphate-mannose-protein mannosyltransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 538 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 65 to 83 (19 residues), see Phobius details amino acids 90 to 109 (20 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details amino acids 142 to 161 (20 residues), see Phobius details amino acids 173 to 201 (29 residues), see Phobius details amino acids 213 to 233 (21 residues), see Phobius details amino acids 265 to 285 (21 residues), see Phobius details amino acids 297 to 316 (20 residues), see Phobius details amino acids 322 to 343 (22 residues), see Phobius details amino acids 355 to 377 (23 residues), see Phobius details PF02366: PMT" amino acids 42 to 245 (204 residues), 29.1 bits, see alignment E=7.7e-11 PF13231: PMT_2" amino acids 67 to 231 (165 residues), 59.7 bits, see alignment E=4.1e-20

Best Hits

KEGG orthology group: None (inferred from 74% identity to vap:Vapar_5573)

Predicted SEED Role

"Polymyxin resistance protein ArnT, undecaprenyl phosphate-alpha-L-Ara4N transferase; Melittin resistance protein PqaB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (538 amino acids)

>GFF6746 dolichyl-phosphate-mannose-protein mannosyltransferase family protein (Variovorax sp. SCN45)
MSRPSSAWWNSPRPLWLIAALFAWLLATAWVRPLMAPDEGRYGGVALAMLHSGDWLVPRL
DGLPFFHKPPLFYWIGAAAMSLTGPTEWAARLPSIIGAGVAAAALFLFLRRWSTAWQALL
STVVLVTTPFFFLGAQFANLDMLVAGCISATVLLGAGAALARERDEPWRALLAGAYLMAA
AGLLAKGLIGLVLPGAVLVLWCAATRKTVVLKLALWLPGWAVLLAVAGPWFVAMQLKYPE
FFDYFVITQHFRRFASSGFNNEHPFWFYIPVLAVLTLPWFAWVFVPRGKNGEARSRLSDV
DWLMWIWLVVIVAFFSMPRSKLVGYVLPALPPLAYLVAQRVLAGRVVEKMLPRMRATAVA
AAVLCVACVGAVAIYSVPPGTRLRLPAGQVVAPGDQVMMLDSYYYEIPFYWNLRSPVLIS
DDWKAAATDTRDNWRKEIYDASRFEPARADATLVNRTELAPVLCVPHTTWLVGPIASQLS
NPWLGKAQVVALNESIAAWRFPGSATSDPGCLGTAAAAASTTTAPSPSAPVPKTNGND