Protein Info for GFF673 in Variovorax sp. SCN45

Annotation: Lysophospholipase L1 and related esterases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF00657: Lipase_GDSL" amino acids 210 to 413 (204 residues), 89 bits, see alignment E=4.9e-29 PF13472: Lipase_GDSL_2" amino acids 213 to 408 (196 residues), 98.1 bits, see alignment E=9.2e-32

Best Hits

KEGG orthology group: None (inferred from 83% identity to vpe:Varpa_2447)

Predicted SEED Role

"Lysophospholipase L1 and related esterases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (423 amino acids)

>GFF673 Lysophospholipase L1 and related esterases (Variovorax sp. SCN45)
MTASRFTSLIRRGAFALSLAGAVAASAAEPASTHWSPSWMASTQPIWSGDFALPPGLPFQ
FNRQTVRQVARLSIGGTRLRVVISNEGGTSPLHIGAAHVARHAEGSAIAEGSDRPLRFGG
QAEVTVPPGARLVSDPVDIALPPLGEVAVSLYLPRPSQPAGFHFDARQTAYLADGDLTAA
PRMPVAASQWSTRVYVSGLIVETQKPPTTVVTLGDSLTDGNGSTPGANTRWPDALAERLA
VRDVAVLNAGISGGRLLKDGMGRAGLERAGRDVFAQPGVRAMVVLLGTNDIGWPGGPFAP
AEPAMRAKELIQGFRQLIEMAHAHNVRIVAGTIPPNEGALKGTPLEGHYSPEKDKVRQAV
NRWIRESGAFDALVDFDALLRDPAHPSRLKAAMDSGDHLHPGDAGYKAMAAAIDLDALLG
IAP