Protein Info for GFF6712 in Variovorax sp. SCN45

Annotation: ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 PF00005: ABC_tran" amino acids 31 to 195 (165 residues), 94.8 bits, see alignment E=1e-30 PF13304: AAA_21" amino acids 162 to 230 (69 residues), 29.7 bits, see alignment E=1.1e-10 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 244 to 334 (91 residues), 70.8 bits, see alignment E=4.1e-24 PF08352: oligo_HPY" amino acids 246 to 315 (70 residues), 51.9 bits, see alignment E=1.3e-17

Best Hits

Swiss-Prot: 48% identical to Y1052_BRUA2: Putative peptide import ATP-binding protein BAB2_1052 (BAB2_1052) from Brucella abortus (strain 2308)

KEGG orthology group: K02031, peptide/nickel transport system ATP-binding protein (inferred from 94% identity to vap:Vapar_1217)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (346 amino acids)

>GFF6712 ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) (Variovorax sp. SCN45)
MTTNANNTPRLAVSNLSTSFPTEDGLVRSVADVSFSIQPGKTTALVGESGSGKSVTSLTL
MRLLPKTANAQVSGSASFVTREGKTLDLLRIGEREMRSLRGNQLSMIFQEPMTSLNPVFT
IGEQIAESVRLHKGLDRKAAMAHARRMLELVEIPAAAQRIDEYPHQLSGGMRQRVMIALA
MACDPTLLIADEPTTALDVTIQAQILELMRRLQAETGMSILFITHNLGVVAHHADDVVVL
YAGRVVESAPVRPLFVQPEHPYTQGLLACLPGKARLPSQPKPKRLFAIRGQVSSPLAPPP
GCAFEPRCDQALAECSAAMPPLIETQHGREARCVRVQPVQPLARVA