Protein Info for GFF6682 in Variovorax sp. SCN45

Annotation: Efflux ABC transporter, permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 transmembrane" amino acids 30 to 48 (19 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details amino acids 208 to 230 (23 residues), see Phobius details amino acids 247 to 270 (24 residues), see Phobius details amino acids 278 to 301 (24 residues), see Phobius details amino acids 469 to 489 (21 residues), see Phobius details PF12679: ABC2_membrane_2" amino acids 17 to 491 (475 residues), 87.4 bits, see alignment E=1.6e-28 PF12040: DUF3526" amino acids 361 to 458 (98 residues), 69.6 bits, see alignment E=7.2e-23

Best Hits

KEGG orthology group: None (inferred from 87% identity to vpe:Varpa_4177)

Predicted SEED Role

"Gll1302 protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (497 amino acids)

>GFF6682 Efflux ABC transporter, permease protein (Variovorax sp. SCN45)
MNDNKPLHPPQGRRLLAVMRQECRLMLAERTLWAVGALFLLLVAYALGNGLVQTASRDRA
QAAVAQADSDTRAAQRVLLTGILAGTAQPTPFENPADPSRMTSSYGGQHALLPTAPLGPV
ALGQSDLFPSQFQVTGQSRVVFMNPSDIESPWHLLSGHFDLAFVIVYLLPLLIFALSYNL
LSAERENGTLRLLLSQPLRLRTLLAGKLSVRAAVLLGPAVLLPVAVLLVARQAGLGGTGS
GVGGATLWWALLVGAYALFWFALVVAVNAFGASSATNAMVLVIAWVMLVLVAPVLLNLAV
TLASPAPSRTELATRQRIVTAEAMKRHADLMSTDYQHVGRGAILVPRDGKIEIAGRLLGN
YLIEKEVDEAIKPELDRFDAQQAGQQALLGRFSAVSPAAVAYEGMTALAGNGTRRQARFE
SQVVAYHAAWKQFFFPRIDARDALAPADFDRIPVFAWQEEPPGLLRGQAAWAVLQLLVPS
LLLFGLAAWRLRRFSVA