Protein Info for GFF655 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Sigma-54 activated regulatory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 409 PF01590: GAF" amino acids 102 to 220 (119 residues), 31.9 bits, see alignment E=1.8e-11 PF02954: HTH_8" amino acids 369 to 402 (34 residues), 39.2 bits, see alignment 4.8e-14

Best Hits

KEGG orthology group: None (inferred from 57% identity to vap:Vapar_5019)

Predicted SEED Role

"Sigma-54 activated regulatory protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (409 amino acids)

>GFF655 Sigma-54 activated regulatory protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MPHPVNGQANTPRQLFFQTTEQRTALARQRFFDEGTRPSGLVGEAVIQSWLRCTSAHQLP
TDLVSFEQVTRSRAHASLNRNRQLLQAGNLELNHMEAALAGTDCRVLLTDAQGVIIHATQ
LPAAREHPLLKTASRVGVNLTEGQVGTNAPGIVVRTGEACTVTGAEHFFQCLQTLHCAAA
PIRDIHGQLAGVLDVSIEAGRFHFDAASVVGMYATTIENRLLQLQSVEHLVLHFQASPTM
LGTPMEALAGIDAGGRVLWLNGAGRRLTGCRMDQRHTVDEVFGVALERLLALSRQHQAQT
LRLPNGLGVWMTGALTTGDGADFKHAVAVSQPAPEAVEAVAPPAVETPAPAEAVHEGTPQ
ATLLDHKQRLIESTLAACGGNIAKAARALGVSRGMLYRRLQKAPAQDAG