Protein Info for GFF6472 in Variovorax sp. SCN45

Annotation: membrane efflux protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 397 transmembrane" amino acids 36 to 62 (27 residues), see Phobius details amino acids 70 to 87 (18 residues), see Phobius details amino acids 93 to 111 (19 residues), see Phobius details amino acids 130 to 151 (22 residues), see Phobius details amino acids 163 to 188 (26 residues), see Phobius details amino acids 208 to 229 (22 residues), see Phobius details amino acids 242 to 265 (24 residues), see Phobius details amino acids 273 to 291 (19 residues), see Phobius details amino acids 297 to 319 (23 residues), see Phobius details amino acids 331 to 352 (22 residues), see Phobius details amino acids 359 to 378 (20 residues), see Phobius details PF07690: MFS_1" amino acids 15 to 348 (334 residues), 98.3 bits, see alignment E=2.3e-32

Best Hits

KEGG orthology group: K08223, MFS transporter, FSR family, fosmidomycin resistance protein (inferred from 40% identity to lxx:Lxx15890)

Predicted SEED Role

"membrane efflux protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (397 amino acids)

>GFF6472 membrane efflux protein (Variovorax sp. SCN45)
MNKRRLGLLTGTHAVNDLYQGLVPALLPFMVLERGYSYTAVAGLMLAATGLSSVVQPLFG
LYADRHPRGWLVPTGFLVAALGVVLAGLSQSYLLTWIAMVLCGLGIAAYHPPATVAARAA
GGASQKAMSVFSVGGTIGASFAPVLAATVVGGGSLSRSYLLGVPALAMGVVWMVANAGSG
AASAASAAAAARKAGGQVLKPHNDWRAFSLLVLTIIGWSIPYVTVLSMLSLRITRDLHGT
AFQGAAALTSFTAAGAVGTLLGGWLGDRIGRMGTIRAGYLFALPSLAGVVLAPNAGWALA
CTALLGMCMFLPFAAQVTLAQDYLPRNPATASGITLGLALSVGGLVSPLFGMLSDARGLG
VTLTAVLCVLCVATVLALRLRNRSMQAMPAEVEGAAA