Protein Info for GFF639 in Sphingobium sp. HT1-2

Annotation: Catalase KatE (EC 1.11.1.6)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00199: Catalase
  • amino acids 8 to 389 (382 residues), 619.8 bits, E=2.1e-190
• PF06628: Catalase-rel
  • amino acids 415 to 475 (61 residues), 69.3 bits, E=2.6e-23

Best Hits

Swiss-Prot: 83% identical to CATA_BRUME: Catalase (katA) from Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 83% identity to oan:Oant_3054)

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethanol degradation IV (3/3 steps found)
• superoxide radicals degradation (2/2 steps found)
• methanol oxidation to formaldehyde IV (1/2 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.6

Protein Sequence (499 amino acids)

>GFF639 Catalase KatE (EC 1.11.1.6) (Sphingobium sp. HT1-2)
MVDKPVMTTSAGAPIADNQNSLSAGPRGPLLLQDYQLLEKLAHQNRERIPERVVHAKGWG
AYGTLTITGDISKYTKAKALQPGAQTPMILRFSTVAGELGAADAERDVRGFAMKFYTPEG
NWDLVGNNTPVFFVRDPLKFPDFIHTQKRHPRTNLRSPTAMWDFWSLSPESLHQVTILMS
DRGLPTDVRHINGYGSHTFSFINDAGERFWVKFHFKTMQGHRHWTNEEAADVVGRTREST
QEDLFEAIEKGDFPKWKMQVQIMPELDADKTPYNPFDLTKVWPHADYPPIDVGVLELNRN
ADNYFAEIEQAAFSPSNIVPGIGFSPDKMLQARIFSYADAHRHRIGTHYEALPVNAPKCP
VHHYHKDGAMRFFPNNPNPAAYYEPNSFGGPVEDQRFLEPPLKISGDADRYNHREGNDDF
GQPRALFNLFDDAQKARLFANIAAAMGDIPDEIEERQCRLFDQVHPDYGAGVRQARATIK
DRNPSISAPTDALLADASS