Protein Info for GFF6373 in Variovorax sp. SCN45

Annotation: T6SS component TssA (ImpA)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 363 TIGR03363: type VI secretion-associated protein, ImpA family" amino acids 7 to 353 (347 residues), 252.4 bits, see alignment E=5.3e-79 PF06812: ImpA_N" amino acids 14 to 135 (122 residues), 118.2 bits, see alignment E=1.1e-38

Best Hits

KEGG orthology group: K11902, type VI secretion system protein ImpA (inferred from 81% identity to vpe:Varpa_2898)

Predicted SEED Role

"Uncharacterized protein ImpA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (363 amino acids)

>GFF6373 T6SS component TssA (ImpA) (Variovorax sp. SCN45)
MRLSPSEIELLQSPVEGPHPCGEDLEYDPDFMALQQATTGKREQQFGTTIIPAEPPDWAR
VERIAKQLCSRTRDLRVLVPLTLAWTENRGLPGYVEGLQLVDAVLQKFWDDVHPRVTEDG
FEDPLPRMNALAALAEAEGLGRSVRDARLLDDGGASMTLRQVEALLDSSKTDQIDYPGGI
GRLRDAARRAQEKAAAPVVALREALELLQRIRETSERALGQSWAPDFSRLERSLRTVVQL
LPEQSQTDQAEAVPPHSPVGSDDNAQLPSAANGTAESVGMGLRAARVKDIEISSRDDVQV
LLEKACQYLERTEPSHPSPMLIRRAQRLLDLNFFQIIEELVPEGLQKIESLAGRPLNGGS
GTQ