Protein Info for GFF6352 in Variovorax sp. SCN45

Annotation: T6SS component TssM (IcmF/VasK)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1219 transmembrane" amino acids 14 to 34 (21 residues), see Phobius details amino acids 46 to 65 (20 residues), see Phobius details amino acids 473 to 494 (22 residues), see Phobius details TIGR03348: type VI secretion protein IcmF" amino acids 15 to 1217 (1203 residues), 1221.5 bits, see alignment E=0 PF14331: IcmF-related_N" amino acids 210 to 477 (268 residues), 292.3 bits, see alignment E=4.8e-91 PF06761: IcmF-related" amino acids 536 to 843 (308 residues), 295.4 bits, see alignment E=9e-92 PF06744: IcmF_C" amino acids 1095 to 1200 (106 residues), 108.2 bits, see alignment E=3.6e-35

Best Hits

Predicted SEED Role

"IcmF-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1219 amino acids)

>GFF6352 T6SS component TssM (IcmF/VasK) (Variovorax sp. SCN45)
MLRAIFRFLIGRDLWVFLGLVALAFLIWIIGPAIAVGRYRPLEDEIVRIAVIALMFAIWL
ARLVYRKWRERRLNAQLLNQLRTPSKKEKEAKPEDAPEIKELQSGFTDATAILKNMRFGQ
GADGKPASRFSVFDRQYLYQLPWYIFIGAPGSGKTTALVNSDLDFPLADQLGKAAVRGIG
GTRNCDWWFTNEAVLIDTAGRYTTHESNRETDEGEWKGFLELLKKFRPRQPINGAILTIS
IADLPLADDAQRARHAMALRKRLLELRNDLGIDFPVYVLVTKTDLLAGFNEYFGSLGRAE
RQQVWGFTFPIEGNAANKAAKGAAPLKGGDLRERFHQEYRLLHQRLDERLPELLAAEPDP
MRRAQAYLLPQQFASFEDILGTFLADVFNPSKFEAASMLRGVYFTSGTQEGTAFDRVMGA
IKRYLQVNAPPAPPPGPGKSYFLKELLQQVIFRDAGVAGTNLRWYRRKRAIDIAGYSVIG
VLLVLFLGACVNSWRNNKDYVAEVDGNAKAFNKAAARGELPTVVDSGGDIASSLLILDRL
RDLPKSSHFDVSDPPLSYRFGLYQGEKLQAATDGVYQRALETVLLPQAAQRVEQSLREAS
KNDAEYSYEALKAYLMLFDAERYDADFLQAWLLSDVDRKIGASLTREQRTNLESHLKALF
AGRVLTSPFAKDERLITQTRERLAGVPLAQRSYARLRRILLQTSPPNAFSIAEAGGAESA
LVIRRASGKPLTDGIPTLFTYRGYWDIFDKRMAETTLSLEQEDRWVLQIRAPGIADITSR
ELLLREVRRLYLTDYIRVWDEYLTDIRLADSRSLLQSIQMTRVLSTSESPMSRIIRGAAR
ETDLLRNHDEAARGLLDQAQNRVASTRERIEQLIGQPDGSQRRNARVDRPESLVDNHFEP
LRRMVTAPKQGGQAPIDATAALINELYTFLTATDTALRSGNIPPSSDAVTKVQAEAGRLP
VPFQGMLNDLSATASSKAAAVTRQNIGQSAAASIGSFCNQAIAGRYPFSRGSNRDVASGD
FAQLFAPGGMMDDFFQKNLITQVDTSVNPWAFKRGVDGSAAGRSAYLDSFQKAQAIRDVF
FSGMAGGRTPSFTLDIRPEDMDAALTQFTLDIDGQTVRYAHGPQAPSTVKWPGPRNSNQV
RLQVTTANGTPAGGIVTEGPWALHRLFDKASISSGSSPESFNATFDLQGKKVVLAVTANS
VYNPLRLPQMNSFSCPGKS