Protein Info for GFF6331 in Variovorax sp. SCN45

Annotation: D-octopine dehydrogenase (EC 1.5.1.11)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF03807: F420_oxidored" amino acids 7 to 104 (98 residues), 24.1 bits, see alignment E=9.4e-09 PF01210: NAD_Gly3P_dh_N" amino acids 8 to 105 (98 residues), 26 bits, see alignment E=1.7e-09 PF02558: ApbA" amino acids 8 to 154 (147 residues), 27.4 bits, see alignment E=4.6e-10 PF02317: Octopine_DH" amino acids 185 to 326 (142 residues), 121 bits, see alignment E=9.2e-39

Best Hits

KEGG orthology group: None (inferred from 83% identity to vap:Vapar_0420)

Predicted SEED Role

"D-octopine dehydrogenase (EC 1.5.1.11)" (EC 1.5.1.11)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (356 amino acids)

>GFF6331 D-octopine dehydrogenase (EC 1.5.1.11) (Variovorax sp. SCN45)
LNKSAYRVGIAGTGAIALASAAWLRQAGHGVTVWSPGGQGAQALRTQALEAGGIQSFSVN
VEVADDPAGLCAASDVLLLALPVNGHRRVMDALLPFLRDGQTVIVSSMASLSSLYLHEAA
HRAGRQITVASFGTTVLTARRESGTQVRVMTRRKAVGVSALPGARVGEAVALCAELFGDG
FFPQESALASALANVNPQSHGPLAVFNWTRIERAENWPQYHCMTPGVSRAIEALDRERRA
VAKAFGIEVGPIEAHFARSFGTTAEKLEDIAAELHAKRGGPPGPTQVDTRYVSEDMPYGL
AFVEALGAIAGVPTPATRTIVDAASLVNGIDYRRENDLLEPLGLARESVAGLLARL