Protein Info for GFF6324 in Variovorax sp. SCN45

Annotation: Kup system potassium uptake protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 649 transmembrane" amino acids 35 to 57 (23 residues), see Phobius details amino acids 74 to 98 (25 residues), see Phobius details amino acids 127 to 150 (24 residues), see Phobius details amino acids 166 to 184 (19 residues), see Phobius details amino acids 196 to 216 (21 residues), see Phobius details amino acids 240 to 260 (21 residues), see Phobius details amino acids 272 to 292 (21 residues), see Phobius details amino acids 312 to 338 (27 residues), see Phobius details amino acids 364 to 384 (21 residues), see Phobius details amino acids 391 to 413 (23 residues), see Phobius details amino acids 420 to 441 (22 residues), see Phobius details amino acids 450 to 467 (18 residues), see Phobius details PF02705: K_trans" amino acids 40 to 570 (531 residues), 726.8 bits, see alignment E=7.5e-223

Best Hits

Swiss-Prot: 79% identical to KUP_POLNA: Probable potassium transport system protein kup (kup) from Polaromonas naphthalenivorans (strain CJ2)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 95% identity to vpe:Varpa_0451)

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (649 amino acids)

>GFF6324 Kup system potassium uptake protein (Variovorax sp. SCN45)
MAPERLPWILRVSDASIEAASPFPIDLVSAPKTISAGLIVGAIGVVYGDIGTSVLYAVKE
VFGHGHVPFTVENVYGILSMFFWTLTVIVSIKYVVLVLRADNEGEGGLVAMLALASRAVA
DKPRLRHLLLVVGIFGTSLFYGDGVITPAISVLSAVEGLEVVSPHFTHYVIPLTLVVLFC
LFVVQKRGTAGIGKFFGPVTLVWFLSIAVLGVSQIVHHPEILKALNPFYALKFIWDNPGT
SFILLGATVLCVTGAEALYADLGHFGKSPIRIAWFSVVMPALTLNYFGQGALLLENPEAV
KNPFFMMAPEWALIPLVLLATLATVIASQALITGAFSVTRQVIQLGYLPRLNIEHTSVRT
AGQIYIPLVNWGLFVAIVLAVVMFRSSSSLAAAYGIAVTTDMLITTVLTFFVIRYAWKLP
LLLCIGSTAVFFFVDFMFFASNLLKLFEGGWFPLMIGGFVFTLMITWKEGRRLMGEAQHA
DAIDLKSFLDSVFVSPPVRVDGTAVFLTAEPGVVPNALLHNLKHNKVLHEQNMFVTVRNH
EVPWIPMDKRIEIEALGHHCWQITVHYGFKNDIDLPRALEHARMRGCQLEAMTTSYFLSR
DVVIPTLGSGMAPWREKLFAQMHHNASGAAAFLGLPNNAVVELGSKIEI