Protein Info for GFF6306 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 transmembrane" amino acids 28 to 49 (22 residues), see Phobius details amino acids 72 to 92 (21 residues), see Phobius details amino acids 102 to 122 (21 residues), see Phobius details amino acids 128 to 148 (21 residues), see Phobius details amino acids 160 to 182 (23 residues), see Phobius details amino acids 188 to 207 (20 residues), see Phobius details amino acids 238 to 262 (25 residues), see Phobius details amino acids 281 to 303 (23 residues), see Phobius details amino acids 315 to 334 (20 residues), see Phobius details amino acids 340 to 360 (21 residues), see Phobius details amino acids 372 to 398 (27 residues), see Phobius details amino acids 406 to 427 (22 residues), see Phobius details PF07690: MFS_1" amino acids 41 to 386 (346 residues), 115.7 bits, see alignment E=1.2e-37

Best Hits

KEGG orthology group: None (inferred from 83% identity to vap:Vapar_0450)

Predicted SEED Role

"Major facilitator family transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (439 amino acids)

>GFF6306 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MNPNAAPKPAERTGDAAPRSRLSRFSHWSASTTAMLVALATAFALSQAFRTVGAMMATPL
SQNFGLTPQQLGMWAGTFHFTFGVMQLGMGVSIDMFGVRRTVLSAFPLAIAGAVLCTMAP
SFHALLLGQALIGVGCAPAFLACTVFIARHFDAARFTAMSGLVMSMAGMGILFTGTPLAL
LIEAASWRAGYAALAGFAVLSWLVIFWRVREPARTVVHDGMQPAPAERQSLRKAVRELLP
LFAMPHTLGLLCFACVSYAAFITLRGLWLGPVLHERHGLSLVASGNVALVMTVAGMISPA
LFGRMDPGGARRGRWMMGCAVAGALMFGAMALTHSAAIDIGLPIIYGLLSGYSVLQYAYT
KNAYPAEMTGRAMALLNMAMFLGVSLMQWTTGVAASWAVTHGAEPFRAVFLTVAGMLAVG
TLAFLVLPRSHGGQSSVKR