Protein Info for GFF6299 in Variovorax sp. SCN45

Annotation: BUG/TctC family periplasmic protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF03401: TctC" amino acids 50 to 322 (273 residues), 270.5 bits, see alignment E=6.9e-85

Best Hits

Swiss-Prot: 39% identical to YCLC_PSEPU: UPF0065 protein in clcB-clcD intergenic region from Pseudomonas putida

KEGG orthology group: None (inferred from 62% identity to reu:Reut_B4957)

Predicted SEED Role

"Tricarboxylate transport protein TctC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>GFF6299 BUG/TctC family periplasmic protein (Variovorax sp. SCN45)
MQSITRRALLACAAAAACLPAASALADTAWPDKPVRLVVPYTPGGATDIVARLIAQKVMD
DTKWTFIVDNRAGGNGNIGMDVVAKAKPDGYTIGLGQTANLAINPTLFPKMPYDALKDLV
PVAVVASQPVVLVVRTEAPYKSLAELVAAAKAKPGEIKQALAGTGTLGHMAGEVLAKRAG
FKVLNVPYKGAAPAITDLLGGQTDYMFATPQGALSMVKGGKLRALAVTSAKRLPVMPDVP
TVGESYQGFEAVDWKAIVVPTGTPADIVKKLNAAIGKALAKPATISQLLAEGSTPGGGSP
EQAAQYIKAEHARWGAAVREAGVRPE