Protein Info for GFF6270 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 transmembrane" amino acids 29 to 50 (22 residues), see Phobius details amino acids 62 to 86 (25 residues), see Phobius details amino acids 93 to 116 (24 residues), see Phobius details amino acids 123 to 143 (21 residues), see Phobius details amino acids 151 to 174 (24 residues), see Phobius details amino acids 181 to 199 (19 residues), see Phobius details amino acids 220 to 238 (19 residues), see Phobius details amino acids 244 to 262 (19 residues), see Phobius details amino acids 283 to 305 (23 residues), see Phobius details amino acids 316 to 334 (19 residues), see Phobius details amino acids 346 to 365 (20 residues), see Phobius details amino acids 377 to 399 (23 residues), see Phobius details amino acids 420 to 442 (23 residues), see Phobius details amino acids 455 to 474 (20 residues), see Phobius details PF07690: MFS_1" amino acids 34 to 430 (397 residues), 101.3 bits, see alignment E=5.4e-33 PF00083: Sugar_tr" amino acids 62 to 198 (137 residues), 23.7 bits, see alignment E=2.2e-09

Best Hits

KEGG orthology group: None (inferred from 87% identity to vpe:Varpa_0518)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (483 amino acids)

>GFF6270 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSSSSAALRPPPPTAGWGELFSGRNGWRALALTGGVALHAINVHIVTTVLPSVVREIGGL
DWYAWSTTLFVVGSILGATLSVRLLAVLGPRGACLAALAVFSAGSIGCALAPAMPWMLAG
RTVQGLGGGLLAALSYGLIQLVFEQRLWPRAVALVSGMWGVATLCGPAVGGLFAQAGHWR
WAFWFLLPVAAAQAVLVLVQLRPSAGVTHTRPATMPRVPGPQIGLLAASVLVIAASGLLS
DLLWQAVGVLLGLAIGFAATRIDRDAVVRVLPTGAYSMRAPLGAIYASVALLLIGTTTEI
FVPYFLQLLHGHSPLAAGYLTAAMAGGWSAGSLLSSGRSGAGADRMLRAGPVICTLGLMA
LAWLLPSPGVFGAGLETLVVAVALAAVGLGVGIGWPHLLTRVMSLAPKGEEGLASASITT
VQLYGMAVGAAVAGLVANAAGLTTPGGVEGARSASVWLFASFALAPALAVWLAYRAVAAR
RGW