Protein Info for GFF6256 in Variovorax sp. SCN45

Annotation: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL (EC 2.7.8.37)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 TIGR02324: phosphonate C-P lyase system protein PhnL" amino acids 5 to 230 (226 residues), 305.9 bits, see alignment E=7.7e-96 PF00005: ABC_tran" amino acids 29 to 186 (158 residues), 96.7 bits, see alignment E=9.5e-32

Best Hits

KEGG orthology group: K05780, putative phosphonate transport system ATP-binding protein (inferred from 91% identity to vap:Vapar_6093)

Predicted SEED Role

"Phosphonates transport ATP-binding protein PhnL" in subsystem Alkylphosphonate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (237 amino acids)

>GFF6256 Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL (EC 2.7.8.37) (Variovorax sp. SCN45)
MTLPMLQLQGVAKRFTLHHQNQLELSVFDEVDLSVSAGECVVLDGASGLGKSTLLKLVYA
NYRASAGRITVQSATGPVDVTEVTPRELVQLRRDTIGYVSQFLRVIPRVAALDVVAEPLA
EDAGDDPAGIEAAREEARRWLTRLRIPERLWHLPPATFSGGEQQRINIARNMIKPKPLLL
LDEPTASLDAANTDTVIALIREATARGAATVGIFHDAEVGAAVATRRVNVGEFRSQP