Protein Info for GFF6239 in Variovorax sp. SCN45

Annotation: Catalase KatE-intracellular protease (EC 1.11.1.6)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 739 PF00199: Catalase" amino acids 49 to 433 (385 residues), 619.2 bits, see alignment E=6e-190 PF06628: Catalase-rel" amino acids 464 to 526 (63 residues), 84.2 bits, see alignment E=1.1e-27 PF18011: Catalase_C" amino acids 571 to 732 (162 residues), 75.5 bits, see alignment E=7.1e-25 PF01965: DJ-1_PfpI" amino acids 572 to 683 (112 residues), 40.6 bits, see alignment E=4.7e-14

Best Hits

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 91% identity to vpe:Varpa_0535)

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (739 amino acids)

>GFF6239 Catalase KatE-intracellular protease (EC 1.11.1.6) (Variovorax sp. SCN45)
MKDSSKSPMTPQNKAAAGRRASASKAGDGSNAKQQQLEGFTVEHPPTLTTNQGLQIPDNH
NSLKAGVRGPTLLEDFILREKITHFDHERIPERAVHARGSAAHGYFQVYKSMSQFTCADF
LQDPDQKTPVFVRFSTVAGSRGSADTVRDVRGFAVKFYTREGNYDLVGNNIPVFFIQDAM
KFPDLIHAVKPEPHHEMPQAASAHDTFWDFASLMPESTHMLMWAMSDRAIPRSLRMMEGF
GVHTFRFINSRGESHFVKFHWKPKLGIHGLVWDEAQKIAGKDADFHRRDLWEAIENGDFP
EWELGVQMIPQDKEHSLGFDLLDPTKLIPEEMVPVQKIGKLVLNRNPDNFFAETEQVAFH
PGHVVPGIDFSNDPLLQGRLFSYTDTQISRLGGANFHELPINKAVCPFHNMQRDGMHRQT
IARGQVAYEPNTLGSGAEFRVDGGSHGFQSFPEEIDPPKVRRRSASFDDHFTQARLFFNS
QSAAEKEHIIAAFRFELSKLEVPAIRQRMVDNLAHVDEKLARRVAEPLGIGEPDAKAAAG
RAGFREHRMTLPIDESPALSMADTGDGTIRTRKIAILVADGVDSASLKPIRDALEQAGAQ
CKIVGPRLGTVASASKRQIDVDMTFANTPSVMFDAVLVPAGSESAAAMAGIGDAVHFVLE
AYKHCKAICTVGEGVRLLSTLGIAADLPQADAPAGVVVAATPVTNMGDTTAATQVANDFI
AAIAKHRHWDRANIDAVPA