Protein Info for GFF6208 in Variovorax sp. SCN45

Annotation: Cytosine/purine/uracil/thiamine/allantoin permease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 transmembrane" amino acids 53 to 76 (24 residues), see Phobius details amino acids 81 to 102 (22 residues), see Phobius details amino acids 123 to 127 (5 residues), see Phobius details amino acids 129 to 131 (3 residues), see Phobius details amino acids 133 to 160 (28 residues), see Phobius details amino acids 173 to 196 (24 residues), see Phobius details amino acids 208 to 226 (19 residues), see Phobius details amino acids 247 to 268 (22 residues), see Phobius details amino acids 288 to 312 (25 residues), see Phobius details amino acids 332 to 354 (23 residues), see Phobius details amino acids 369 to 389 (21 residues), see Phobius details amino acids 395 to 419 (25 residues), see Phobius details amino acids 449 to 469 (21 residues), see Phobius details amino acids 475 to 491 (17 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 44 to 480 (437 residues), 306.6 bits, see alignment E=1.5e-95

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 97% identity to vap:Vapar_3935)

Predicted SEED Role

"Hydantoin permease" in subsystem Hydantoin metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (497 amino acids)

>GFF6208 Cytosine/purine/uracil/thiamine/allantoin permease family protein (Variovorax sp. SCN45)
MSTVVSQAPAGASEAGIAPHAESNAVIKPGYHPRLTNEDLAPLKKQTWGQYNIFAFWMSD
VHSVGGYITAGSLFALGLSSWQVLVSLLVGIVIVQFFCNLVAKPSQVTGVPYPVVCRAPF
GVLGANIPAIIRGLIAVAWYGVQTYLASAAFMVLALHMAPSLAPYADVAQHGFVGLSALG
WVAFMVMWVLQAFVFWHGMEAIRKFIDWAGPAVYVVMAVLCGWLVWKAGWSKIDLNLGGI
KFQGWDALPVMLSAIALVVSYFSGPMLNFGDFSRYGKSFDAVKKGNFWGLPVNFVFFSLL
TVITTAATLPVFGELITDPVHTVGKIDSTTAVVLGALTFMIATIGINIVANFVSPAFDFS
NVAPQHISWRTGGMIAAVGSVFLTPWNLYNSPEVIHYTLDVLGSFIGPLFGILIADYYIV
RKQRIDVDALYTMSPKGEYWYSGGYNPKAIQALVPSAIVPILCVMVPTLRGAANYAWFIG
MGLGFILYALLNRSSKT