Protein Info for GFF6194 in Variovorax sp. SCN45
Annotation: ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 48% identical to DPPF_HAEIN: Dipeptide transport ATP-binding protein DppF (dppF) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG orthology group: K02032, peptide/nickel transport system ATP-binding protein (inferred from 86% identity to vap:Vapar_4353)Predicted SEED Role
"Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (271 amino acids)
>GFF6194 ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) (Variovorax sp. SCN45) MSQPTTAGQPLLAVKNLYRHYALPREKLFGPPPTVKALNGVSFDVQAGKSMGIVGESGSG KSTIARLVMALDTPTSGTVSLEGRDLHSLSKEALRVARRDFQMVFQDPYGSLDPRQTVAR IVAEPLEALAETSRAEQRERASEALSAVGLRTTDMDKYPHEFSGGQRQRIAIARALITRP KLIVADEPVSALDVSVQAQVLNLMQDLQQQFGISYLLISHDLAVVNHLCDEVCVVFKGRI VERGRPADLFAHAQHEYTRTLLSAVLHTPSR