Protein Info for GFF6161 in Variovorax sp. SCN45
Annotation: Hydroxymethylpyrimidine ABC transporter, ATPase component
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 42% identical to Y412_METJA: Uncharacterized ABC transporter ATP-binding protein MJ0412 (MJ0412) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
KEGG orthology group: None (inferred from 69% identity to bja:bll4204)Predicted SEED Role
"Hydroxymethylpyrimidine ABC transporter, ATPase component" in subsystem Thiamin biosynthesis
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (267 amino acids)
>GFF6161 Hydroxymethylpyrimidine ABC transporter, ATPase component (Variovorax sp. SCN45) MSAVLQPRMDAQQQVPLIRMRQLRKVYRKRNEEFLAVSDVTMDVDAGDMISLVGPSGCGK STLLKILSGLHGHDGGTLEIGGPDGHGFNAGRDVGMVFQQPLLLKWRTILDNVLLPADIL GLERRAATQRAHELLEMVGLAGFADKLPYELSGGMQQRAAIARALIHDPKLVLMDEPFGA LDALTREKMNLEMLRIWEQSRKTFIVVTHSIQEAVFLGSHCAVLTAGPARMADFFRIDLP EPRKLHVKTSPEFGAYVRRIYDLLGVD